NOR-1 AND NUR77 NUCLEAR RECEPTORS AS TARGETS FOR ANTI-LEUKEMIA THERAPY

摘要

The present invention is directed to the application of nuclear receptor transcription factors as molecular targets for therapeutic intervention in the treatment of myeloid leukemia. More specifically, nor-1 and nur77 nuclear receptors are targets for myeloid leukemia therapy. The figure shows the growth curve of one litter including two nor-1KO/nur77KO mice and their normal littermates that is representative of a number of litters that were weighed daily for a period of two weeks.