Method and apparatus for multi-spectral analysis in noninvasive infrared spectroscopy

摘要

An apparatus for determining the concentration of an organic blood analyte in a body tissue sample, comprising:(a) means for irradiating the sample with incident radiation containing a plurality of distinct, nonoverlapping spectral regions, all of said regions within a wavelength range of 1100 and 5000 nanometers within a beam path;(b) means for collecting reflected radiation emerging from the sample and directing said reflecting radiation along the beam path;(c) diffraction grating means disposed in the beam path for receiving reflected radiation emerging from the sample;(d) a linear detector array for receiving the passed wavelengths emerging from the diffraction grating means;(e) means for converting the detected wavelengths into a signal representative of the intensity of said wavelengths; and(f) means for correlating said signal representative of the intensity of said wavelengths to determine the concentration of the analyte and for measuring the intensity of radiation from said body tissue sample in the near-IR absorption spectrum, especially for water, for at least one of:to provide a reference to detect inaccurate measurements; andto identify ineffective measurements arising from a failure to obtain a proper instrumentation scan of the tissue sample.