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SELF-ASSEMBLED MUSCLE-POWERED MICRODEVICES

机译:自组装肌肉微动装置

摘要

Cultured muscle tissue used as actuators in microelectromechanical systems (MEMS) for mechanical and electrical power generation can either be dissected or cultured from myoblasts and grown in situ. The MEMS is fabricated using conventional techniques (surface or bulk micromachining) and incorporating surface modification techniques and/or anchor structures to favor muscle attachment followed by post-processing to assemble dissected muscle tissue or grow the self-assembling muscle tissue at the desired sites. Initial post processing is done to incorporate PZT devices for energy conversion. Additional post-processing is then done for muscle tissue self-assembling; that includes coating the MEMS with polymers that will either repel or favor the muscle growth, and the culturing on the muscle tissue starting from myoblasts. The system is fueled by adding glucose to the medium in which it is contained.
机译:可以在成肌细胞中解剖或培养用作微机电系统(MEMS)中用于作动力和发电的促动器的培养肌肉组织,然后就地生长。 MEMS是使用常规技术(表面或本体微机械加工)并结合表面修饰技术和/或锚固结构以利于肌肉附着,然后进行后处理以在需要的部位组装解剖的肌肉组织或使自组装的肌肉组织生长的方法制造的。完成初始后处理以合并用于能量转换的PZT设备。然后进行额外的后处理,以进行肌肉组织的自组装。这包括用可排斥或有利于肌肉生长的聚合物涂覆MEMS,以及从成肌细胞开始在肌肉组织上进行培养。通过将葡萄糖添加到其中所含的介质中为系统提供燃料。

著录项

  • 公开/公告号WO2004014212A2

    专利类型

  • 公开/公告日2004-02-19

    原文格式PDF

  • 申请/专利权人 MT TECHNOLOGIES INC.;

    申请/专利号WO2003US22497

  • 发明设计人 MONTEMAGNO CARLO D.;NEVES HERCULES P.;

    申请日2003-08-07

  • 分类号A61B;

  • 国家 WO

  • 入库时间 2022-08-21 22:58:24

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