DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR P2Y10 (P2Y10)

摘要

The invention provides a human P2Y10 which is associated with the hematological diseases, cardiovascular diseases, urology diseases, respiratory diseases, cancer diseases, gastrointestinal diseases and endocrinological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, urology diseases, respiratory diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of P2Y10 as well as pharmaceutical compositions comprising such compounds.