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USE OF QUINAZOLINE DERIVATIVES WITH SRC KINASE INHIBITORY ACTIVITY FOR THE TREATMENT OF HYPERTENSION

机译:喹唑啉衍生物与SRC激酶抑制活性在高血压治疗中的应用

摘要

The invention relates to the use of a Src kinase inhibitor in the production of a medicament for use in the prophylaxis or treatment of hypertension. More particularly, the invention concerns the anti-hypertensive use of a selective Src kinase inhibitor that possess less potent VEGF receptor tyrosine kinase inhibitory properties. The invention also relates to a combination product comprising a Src kinase inhibitor and one or more further anti-hypertensive agents and to the use of Src kinase inhibitors as primary regulators of cardiovascular disease and in the prevention of stroke.
机译:Src激酶抑制剂在制备用于预防或治疗高血压的药物中的用途本发明涉及Src激酶抑制剂在制备用于预防或治疗高血压的药物中的用途。更具体地,本发明涉及具有较低效力的VEGF受体酪氨酸激酶抑制性质的选择性Src激酶抑制剂的抗高血压用途。本发明还涉及包含Src激酶抑制剂和一种或多种其他抗高血压药的组合产品,并且涉及Src激酶抑制剂作为心血管疾病和预防中风的主要调节剂的用途。

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