首页> 外国专利> MATERIALS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS INVOLVING OVERACTIVATION OF GLUTAMATERGIC IONOTROPIC RECEPTORS

MATERIALS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS INVOLVING OVERACTIVATION OF GLUTAMATERGIC IONOTROPIC RECEPTORS

机译:涉及过度活化谷氨酸离子营养受体的神经系统疾病的材料和方法

摘要

The subject invention pertains to pharmaceutical compositions, articles of manufacture, and methods useful for treatment of neurological conditions related to, or which can be affected by, modulation of glutamate receptor (GluR) activity. The treatment can be either prophylactic in nature or to alleviate symptoms of such neurological conditions. The pharmaceutical compositions of the subject invention include an aromatic amino acid (AAA), an analog or isomer of an AAA, or combinatins thereof, and a pharmaceutically acceptable carrier or diluent. Methods of the subject invention involve parenterally administering to a patient at least one AAA, an analog or isomer of an AAA, or combinations thereof.
机译:本发明涉及用于治疗与谷氨酸受体(GluR)活性相关或受其影响的神经疾病的药物组合物,制品和方法。这种治疗可以是预防性的,也可以是减轻这种神经系统疾病症状的方法。本发明的药物组合物包括芳香族氨基酸(AAA),AAA的类似物或异构体,或其组合蛋白,以及药学上可接受的载体或稀释剂。本发明的方法涉及肠胃外给予患者至少一种AAA,AAA的类似物或异构体,或其组合。

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