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Mycoplasma Bovis Challenge Model, Methods for Administering M. Bovis and Methods for Inducing Pneumonic Lung Lesions
Mycoplasma Bovis Challenge Model, Methods for Administering M. Bovis and Methods for Inducing Pneumonic Lung Lesions
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机译:支原体牛分枝杆菌攻击模型,牛分枝杆菌的给药方法和肺炎性肺病变的诱导方法
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摘要
The present invention provides a reproducible M. bovis challenge model and methods for reliably inducing and establishing a disease or disorder caused by infection with M. bovis by administering to an animal an effective amount of a M. bovis culture. The challenge culture of the present invention is administered in an amount sufficient to elicit M. bovis specific cellular or humoral immune responses. The M. bovis challenge model in accordance with the present invention can be used to evaluate the efficacy of potential vaccines.
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