首页> 外国专利> MARKER FOR DIAGNOSING RADIO-RESISTANCE OR RADIATION-INDUCED CANCER, KIT OR MICROARRAY FOR DIAGNOSING RADIO-RESISTANCE OR RADIATION-INDUCED CANCER CONTAINING THE SAME, AND SCREENING METHOD OF DRUGS USING THE SAME

MARKER FOR DIAGNOSING RADIO-RESISTANCE OR RADIATION-INDUCED CANCER, KIT OR MICROARRAY FOR DIAGNOSING RADIO-RESISTANCE OR RADIATION-INDUCED CANCER CONTAINING THE SAME, AND SCREENING METHOD OF DRUGS USING THE SAME

机译:诊断抗辐射或辐射诱发性癌症的标记物,工具包或微阵列,用于诊断包含相同抗癌或辐射诱发性癌症的药物和筛查方法,使用相同的药物

摘要

PURPOSE: A marker for diagnosing radio-resistance or radiation-induced cancer, a kit or microarray for diagnosing radio-resistance or radiation-induced cancer containing the same, and a screening method of drugs using the same are provided, thereby easily finding genes associated with radio-resistance and radiation-induced cancer, and easily screening drugs for prevention or treatment of radio-resistance and radiation-induced cancer. CONSTITUTION: The marker for diagnosing radio-resistance or radiation-induced cancer comprises a nucleotide under NCBI gene bank accession no. X58876 or S93521, wherein the marker may further comprise a nucleotide selected from NCBI gene bank accession no. AF132483, J04806, X52046, AF077003, L33726, X13358, Z14249 and X14194. The screening method of drugs for prevention or treatment of radio-resistance and radiation-induced cancer comprises the steps of: subjecting mammals except for human to radiation; collecting mammal cells from the irradiated mammals and contacting the mammal cells with a testing material; and measuring the expression change of radiation resistance genes comprising the nucleotide under NCBI gene bank accession no. X58876 or S93521.
机译:目的:提供一种用于诊断抗辐射或辐射诱发的癌症的标志物,用于诊断其的试剂盒或微阵列以及包含其的试剂盒和药物筛选方法,从而可以轻松地找到与之相关的基因患有抗辐射和辐射诱发的癌症,并轻松筛选用于预防或治疗抗辐射和辐射诱发的癌症的药物。构成:用于诊断抗辐射或辐射诱发的癌症的标志物包含NCBI基因库登录号为No.的核苷酸。 X58876或S93521,其中标记可以进一步包含选自NCBI基因库登录号No. AF132483,J04806,X52046,AF077003,L33726,X13358,Z14249和X14194。预防或治疗抗辐射和辐射诱发的癌症的药物筛选方法包括以下步骤:使除人类以外的哺乳动物受到辐射;从受辐照的哺乳动物中收集哺乳动物细胞,并使哺乳动物细胞与测试材料接触;并测量NCBI基因库登录号为No.1的包含核苷酸的抗辐射基因的表达变化。 X58876或S93521。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号