Enzymatic Separation of Enantiomers of Lac-2-oxotricyclo (2.2.1.03,5) heptan-7-carboxylic Acid and Lac-2-oxotricyclo (2.2.1.03,5) heptan-7-carboxylic Acid Ester

摘要

The enantiomeric or racemic mixtures of the compounds of the general formula (I) may be prepared in water, optionally in auxiliary solvents, with pork liver, pig pancreas, bovine pancreas, or Candida, Pseudomonas, Mucor, Rizopus and Treating with a protease from Bacillus or in the presence of lipase or esterase from a microorganism such as Aspergillus and;By separating the ester and the acid present in the obtained solution from each other, it can be obtained in isomeric pure form from the enantiomer mixture or the racemic mixture.;In general formula (I) above,;R ¹ is as defined in the specification.