ISOLATED POLYPEPTIDE SHOWING HOMOLOGY RELATIVELY TO COMPLEMENT-RELATED ADIPOCYTE PROTEIN (VARIANTS), HYBRID PROTEIN (VARIANTS), EXPRESSING VECTOR, METHOD FOR PREPARING POLYPEPTIDE, POLYCLONAL ANTIBODY, FRAGMENT OF ISOLATED POLYNUCLEOTIDE (VARIANTS)

摘要

FIELD: biotechnology, biochemistry, molecular biology. SUBSTANCE: invention relates to protein (Zsig 37) that is homologous with complement-related adipocyte protein, polynucleotide fragment that encodes this protein, expressing vector, method for preparing protein and also to polyclonal antibody showing specificity to this characterized protein. Protein and also fragment of polynucleotide encoding this protein take part in dimerization and oligomerization processes, it able to modulate energetic homeostasis and , therefore, can be used for prophylaxis and treatment of disbalnces. EFFECT: improved preparing method, valuable biological and biochemical properties of protein. 15 cl, 4 tbl, 3 dwg, 11 ex