APPLICATION OF FUMARIC ACID DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES

摘要

FIELD: organic chemistry, medicine, molecular pathology. SUBSTANCE: invention proposes the application of one or some compounds among the group consisting of fumaric acid dialkyl esters and monoalkyl esters as free acid or its salts as an agent for treatment of disease caused by damage of oxidative phosphorylation and taken among the group including Parkinson's disease, Alzheimers's disease, Huntington's chorea, pigmentary retinopathy and mitochondrial encephalomyopathy. EFFECT: valuable medicinal properties of compounds, expanded assortment of agents of indicated designation. 10 cl, 1 tbl, 4 ex