PEPTIDE INDUCTION ANTIBODIES FORMATION THAT REACT WITH TWO DIFFERENT BPPCC ISOLATES (VARIANTS), IMMUNOGENIC COMPOSITION, VACCINE FOR PROPHYLAXIS AGAINST INFECTION WITH PIG REPRODUCTIVE- -RESPIRATORY SYNDROME, ANTIBODY, DIAGNOSTIC SET (VARIANTS)

摘要

FIELD: veterinary science, virology, immunology, peptides. SUBSTANCE: invention represents peptide corresponding to antigenic site of two isolates of BPPCC. Peptide is neutralizing, conservative, non-conservative and conformational, it can induce formation of antibodies and it is a component of proteins GP₄ and N encoding by opened frames ORF4 and ORF7 of BPPCC virus. Amino acid sequences identified in these sites can be incorporated to composite of immunogenic composition, vaccine against PPCC and to diagnostic test for PPCC. Diagnostic test and vaccine are used for detection and prophylaxis of pig reproductive-respiratory virus syndrome. EFFECT: valuable properties of peptide and vaccine. 22 cl, 2 tbl, 9 dwg