METHOD FOR PREPARING LABORATORY RAT PERITONEAL MAST CELLS

摘要

FIELD: experimental medicine.;SUBSTANCE: invention can be used for detection of causal-significant allergens in patients with allergic diseases for investigation of mechanisms action of different pharmacological preparations. One-ten minutes before onset of procedure proserin is administrated in rat additionally in the dose 0.1-0.4 mg/kg of weight by intracutaneous route as 0.05% solution. Invention provides elevating yield of mast cells in rats and absence of negative effect on functional and physiological properties of indicated cells.;EFFECT: improved preparing method.;5 cl, 3 tbl, 1 ex