首页> 外国专利> Use of one or more oxygen carriers selected from hemoglobin, myoglobin and derivatives thereof for the treatment of an organ dysfunction due to an acute lack of supply and for the treatment / prevention of tissue damage due to such a disorder

Use of one or more oxygen carriers selected from hemoglobin, myoglobin and derivatives thereof for the treatment of an organ dysfunction due to an acute lack of supply and for the treatment / prevention of tissue damage due to such a disorder

机译:一种或多种选自血红蛋白,肌红蛋白及其衍生物的氧载体在治疗由于严重缺乏供应而引起的器官功能障碍以及治疗/预防由于这种疾病引起的组织损伤中的用途

摘要

The present invention relates to the use of one or more natural or modified oxygen carriers or derivatives thereof, for the treatment of an organ dysfunction due to an acute lack of supply and for the treatment / prevention of tissue damage due to such a disorder. In particular, acute oxygen and / or nutrient deficiency states such as tinnitus, heart attack, stroke, sudden hearing loss, dizziness, placental insufficiency, kidney shock or lung shock can be treated according to the invention. The oxygen carrier (s) can be of human or animal origin and are used as aqueous solutions which, for example, have the naturally present electrolyte concentration or also further salts / additives. The oxygen carrier is used in a concentration of 2 to 200 g / liter of solution, preferably 10 to 80 g / liter, over a period of 1 day (e.g. single administration) up to 6 weeks with multiple administration as required and indication used.
机译:本发明涉及一种或多种天然或修饰的氧载体或其衍生物在治疗由于严重缺乏供应而引起的器官功能障碍以及在治疗/预防由于这种疾病引起的组织损伤中的用途。特别地,可以根据本发明治疗急性氧和/或营养缺乏状态,例如耳鸣,心脏病,中风,突然的听力丧失,头晕,胎盘功能不全,肾脏休克或肺休克。氧载体可以是人或动物来源的并且用作水溶液,其例如具有天然存在的电解质浓度或另外的盐/添加剂。氧载体的使用浓度为2至200克/升溶液,优选10至80克/升,经过1天(例如单次给药)至6周,并根据需要多次给药并使用适应症。

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