Cells, the r - alpha - lipoic acid secrete only some and method for the fermentative preparation of the r - alpha - lipoic acid

摘要

The present invention relates to cells and a process for the preparation of r - α - lipoic acid by means of fermentation. According to the invention, the host organisms strain for the fermentative preparation of r - α - lipoic acid is suitable, is characterized in that it comprises a gene coding for a lipoic acid - synthase overexpressed and the formed r - α - lipoic acid, in free form in the culture medium must be excluded.