3,5 - dioxo - 8 - aza - tricyclo (5.2.1.00,0) decanes - 9 - alkanols methanol, their metal complexes and their use for the enantioselective hydrogenation

摘要

Compounds of the formula I, in the form of their racemates, mixtures of stereoisomers or mainly pure stereoisomers chemistry chemdraw filechemistry mol file;in which ;Y is C₁-C₄alkylene or —SiR₁R₂—; ;X is a carbon atom and A₁ and A₂ independently of one another are hydrogen, C₁-C₁₂alkyl, ;C₂-C₁₂alkenyl, C₃-C₈cycloalkyl, C₃-C₈cycloalkenyl, C₃-C₈cycloalkyl-C₁-C₄alkyl, C₃-C₈cycloalkenyl-C₁-C₄alkyl, C₆-C₁₀aryl or C₇-C₁₄aralkyl; or ;X is a silicon atom and A₁ and A₂ independently of one another are C₁-C₁₂alkyl, C₃-C₈cycloalkyl, C₃-C₈cycloalkyl-C₁-C₄alkyl, C₆-C₁₀aryl or C₇-C₁₄aralkyl; ;A₃ and A₄ independently of one another are hydrogen, C₁-C₁₂alkyl, C₃-C₈cycloalkyl, C₃-C₈-cycloalkyl-C₁-C₄alkyl, C₆-C₁₀aryl or C₇-C₁₄aralkyl; and ;R₁ and R₂ independently of one another are C₁-C₆alkyl, cyclohexyl, phenyl or benzyl, are ligands for metal complexes of the eighth sub-group of the Periodic Table of the Elements, which are suitable as catalysts for asymmetric hydrogenations and transfer hydrogenations of prochiral compounds having carbon/carbon or carbon/heteroatom multiple bonds.