biphasige arzneimiteldosierungsform consisting of many components, which contains substances that can influence the distribution of medicines

摘要

The invention provides a biphasic multicomponent pharmaceutical composition consisting of an oil phase and a water phase, comprising one or more lipophilic or oil carrier, one or more hydrophilic or aqueous carrier, one or more ionic or nonionic type surfactant, one or more cosurfactant, one or more active principle for pharmaceutical use, and a compound able to modify the partition of the active principle between said phases selected from the group consisting of N- methyl pyrrolidone (NMP), isopropyl alcohol, propylene glycol, ethoxy-di-glycol, beta-cyclodextrin, hydroxypropyl beta-cyclodextrin and dimethyl beta-cyclodextrin. The invention also provides a method for making the composition.