首页> 外国专利> USE OF NAD OR ONE OF ITS ANALOGS, SUBSTRATE OF MONO-ADP-RIBOSYL TRANFERASES, FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF CONDITIONS RELATED TO PURINERGIC RECEPTORS

USE OF NAD OR ONE OF ITS ANALOGS, SUBSTRATE OF MONO-ADP-RIBOSYL TRANFERASES, FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF CONDITIONS RELATED TO PURINERGIC RECEPTORS

机译:使用NAD或其类似物之一,单-ADP-核糖基转移酶的底物,制备用于治疗多发性受体疾病的药物

摘要

P The present invention relates to the use of nicotinamide adenine dinucleotide (NAD) or at least one of its analogs, substrate of mono-ADP-ribosyl transferases (ART) in the preparation of a medicament intended to modulate the activity of at least one purinergic receptor, advantageously of the P2X or P2Y type, said medicament being particularly intended for the treatment of pathologies in which the purinergic receptors participate in the pathophysiological process or of pathologies linked to a deregulation of the activity of the purinergic receptors . / P
机译:本发明涉及烟酰胺腺嘌呤二核苷酸(NAD)或其至少一种类似物,单ADP-核糖基转移酶(ART)的底物在制备旨在调节至少一种活性的药物中的用途。一种嘌呤能受体,有利地为P2X或P2Y型,所述药物特别用于治疗其中嘌呤能受体参与病理生理过程的病理或与嘌呤能受体的活性失调有关的病理。

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