Producing substances in Escherichia, useful particularly for preparing amino acids, by culturing a bacterium in which the FIS protein, involved in nucleoid formation, is inactivated

摘要

Producing a target substance (I) comprising culturing a (I)-producing strain of an Escheichia bacterium so that (I) accumulates in the medium or cells and is then recovered, is new. The new feature is that the protein FIS (factor for stimulation by inversion) is not functional in the cells.