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Method of treating parkinson's disease in humans by direct infusion of Glial cell-line derived neurotrophic factor into the Zona incerta
Method of treating parkinson's disease in humans by direct infusion of Glial cell-line derived neurotrophic factor into the Zona incerta
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机译:通过将神经胶质细胞系衍生的神经营养因子直接输注到不透明带中来治疗人类帕金森氏病的方法
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摘要
A method of treating Parkinson's disease in humans is disclosed, wherein glial cell-line derive neurotrophic factor (GDNF) is chronically administered directly to the SNc and at least one subthalamic region or, alternatively, to the SNc, at least one sub thalamic region, and at least one putaminal region of the brain of a human in need of treatment thereof. In one aspect of the present invention the GDNF is infused directly into at least one caudal zona incerta and at least one postero-dorsal putamen of the brain through indwelling intraparenchymal brain catheters connected to an implantable pump.
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