Mutation Actinosynnema pretiosum to increase the maytansinoid production (Actinosynnemapretiosum) Ltd.

摘要

A microorganism is a mutant bacterial strain Actinosynnema pretiosum named (ATCC PTA-3921) of (Actinosynnema pretiosum) species, PF4-4 Ansamaito in improved yields as compared to the strains known conventional the microorganism which can grow under a variety of culture conditions to produce a maytansinoid ansamitocins and new P-3 is and can be, and are cultured in a suitable growth medium above PF4-4 Methods for producing maytansinoid ansamitocin by.