首页> 外国专利> At least mixture formation or hybridization between 2 basic molecules the method of detection which is detected on the basis of the expansion signal in the said backing on the solid backing

At least mixture formation or hybridization between 2 basic molecules the method of detection which is detected on the basis of the expansion signal in the said backing on the solid backing

机译:至少在两个碱性分子之间形成混合物或杂交的检测方法,该检测方法基于所述固体背衬上的所述背衬中的扩展信号进行检测

摘要

A method for detecting at a solid support (3) complexing or hybridization between at least two basic molecules (8 and 9), one of the molecules being initially fixed on support (3), called identifying molecule (8), and the other being in solution in liquid sample (2), called target molecule (9). A solid support for detecting complexing or hybridization between at least two different molecules, a biochip incorporating the support and use of the biochip in a diagnostic test are also disclosed. The method includes: using chemical or biological element (10), specifically bound to the formed complex or hybrid; exciting the complex or the hybrid, so that chemical or biological element (10) releases light signal (11); receiving and transforming light signal (11) into chemical signal (15) at support (3), and detecting electric signal (12) derived from chemical signal (15).
机译:一种用于检测固相支持物(3)至少两个基本分子(8和9)之间的复合或杂交的方法,其中一个分子最初固定在支持物(3)上,称为识别分子(8),另一个为在液体样品(2)中的溶液中,称为目标分子(9)。还公开了用于检测至少两种不同分子之间的复合或杂交的固体支持物,结合了该支持物的生物芯片以及该生物芯片在诊断测试中的用途。该方法包括:使用化学或生物元素(10),其特异性结合到形成的复合物或杂种上;激发复合物或杂种,从而使化学或生物元素(10)释放光信号(11);在支架(3)处接收光信号(11)并将其转换为化学信号(15),并检测从化学信号(15)得出的电信号(12)。

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