首页> 外国专利> METHOD FOR DETECTING AT A SOLID SUPPORT OF COMPLEXING OR HYBRIDIZATION BETWEEN AT LEAST TWO BASIC MOLECULES BASED ON AN AMPLIFIED AT THE SUPPORT

METHOD FOR DETECTING AT A SOLID SUPPORT OF COMPLEXING OR HYBRIDIZATION BETWEEN AT LEAST TWO BASIC MOLECULES BASED ON AN AMPLIFIED AT THE SUPPORT

机译:基于支持度放大的至少两个基本分子之间的复合或混合固相支持的检测方法

摘要

A method for detecting at a solid support (3) complexing or hybridization between at least two basic molecules (8 and 9), one of the molecules being initially fixed on support (3), called identifying molecule (8), and the other being in solution in liquid sample (2), called target molecule (9). A solid support for detecting complexing or hybridization between at least two different molecules, a biochip incorporating the support and use of the biochip in a diagnostic test are also disclosed. The method includes: using chemical or biological element (10), specifically bound to the formed complex or hybrid; exciting the complex or the hybrid, so that chemical or biological element (10) releases light signal (11); receiving and transforming light signal (11) into chemical signal (15) at support (3), and detecting electric signal (12) derived from chemical signal (15).
机译:一种用于检测固相支持物(3)至少两个基本分子(8和9)之间的复合或杂交的方法,其中一个分子最初固定在支持物(3)上,称为识别分子(8),另一个为在液体样品(2)中的溶液中,称为目标分子(9)。还公开了用于检测至少两种不同分子之间的复合或杂交的固体支持物,结合了该支持物的生物芯片以及该生物芯片在诊断测试中的用途。该方法包括:使用化学或生物元素(10),其特异性结合到形成的复合物或杂种上;激发复合物或杂种,从而使化学或生物元素(10)释放光信号(11);在支架(3)处接收光信号(11)并将其转换为化学信号(15),并检测从化学信号(15)得出的电信号(12)。

著录项

  • 公开/公告号EP1412726A1

    专利类型

  • 公开/公告日2004-04-28

    原文格式PDF

  • 申请/专利权人 BIOMERIEUX S.A.;

    申请/专利号EP20020779605

  • 发明设计人 MANDRAND BERNARD;GARNIER FRANCIS;

    申请日2002-08-01

  • 分类号G01N21/64;B01L3/00;G01J1/48;

  • 国家 EP

  • 入库时间 2022-08-21 22:52:41

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