Microfluidic separation device comprising a sample on-column injector of the type

摘要

Microfluidic separation device of the pressure-driven to separate species or biological chemistry from the sample (100-601) the introduction of on-column, ie separation groove accommodating the (115-360) and the stationary phase material (114-561) I and a sample inlet which is disposed between a first end of the column (114A~561A) a second end of (114B~561B) or isolation trenches. Template layer is sandwiched made from a variety of materials, including polymer with (102-408), it is possible to provide a separate groove in one or more microfluidic devices of one. I provide a seal mechanical seal means for sealing selectively the sample inlet of (520,530,606), and the like. I provide a sample injector variety. Separation system including a microfluidic device comprising introducing on-column detector (603) and pressure source (607).