Bone-inducing ability or sustained drug release can be bioactive bioabsorbable type organic-inorganic composite material having a conductivity function

摘要

PROBLEM TO BE SOLVED: To give a bone inducing or bone conductive function having well balanced properties among flexibility, strength, elastic modulus, productivity, reproducibility and shaping processability by improving brittleness, shaping processability and productivity of bioactive calcium phosphate. SOLUTION: This compounded material comprises a structural unit originated from lactic acid and a polyester structural unit originated from a dicarboxylic acid and a diol, and it comprises 2-60wt.% of the lactic acid-based polyester having a weight average molecular weight of 20,000 to 400,000 and calcium phosphate and has a ratio of the lactic acid-based polyester to calcium phosphate of 1/99 to 50/50 by weight. Further, by making the lactic acid based- polyester contain a chelating agent and/or a structural unit originated from an acidic phosphate, a medicinal slow releasability having bone inducing or conducting function improved in stability on blending and shaping processing is attained.