Combination therapy of DAPD and IMDPH inhibitors such as mycophenolic acid or ribavirin

摘要

It has been unexpectedly found that a drug resistant strain of HIV exhibits the behavior of drug-naïve virus when given the combination of a beta-D-1,3-dioxolanyl nucleoside and an IMPDH inhibitor. In one nonlimiting embodiment, the HIV strain is resistant to a beta-D-1,3-dioxolanyl nucleoside.