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Method for assisting the diagnosis of Alzheimer's disease by measuring the amyloid β peptide (X- ≧ 41) and tau

机译:通过测量β淀粉样蛋白(X-≥41)和tau蛋白来辅助诊断阿尔茨海默氏病的方法

摘要

(57) [Abstract] The present invention provides methods useful for assisting in the diagnosis of Alzheimer's disease. The method includes measuring the amount of amyloid β peptides in cerebrospinal fluid of patients with (x- ≧ 41). In general, high levels of peptides, not consistent with a diagnosis of Alzheimer's disease. May provide a positive diagnostic test together with other low level of peptides and, consistent with the disease. Other methods include the step of measuring the amount of both Aβ and tau (x- ≧ 41). High levels of tau and low levels of (x- ≧ 41) Aβ is a positive indication of Alzheimer's disease, on the other hand, low levels of tau and the high level of (x- ≧ 41) Aβ is, the negative of Alzheimer's disease is an indicator.
机译:(57)[摘要]本发明提供了用于辅助诊断阿尔茨海默氏病的方法。该方法包括测量(x-≥41)患者的脑脊液中淀粉样蛋白β肽的量。通常,高水平的肽与阿尔茨海默氏病的诊断不一致。可能与其他低水平的多肽一起提供阳性诊断测试,并与疾病一致。其他方法包括测量Aβ和tau(x-≥41)的量的步骤。高水平的tau和低水平的(x-≥41)Aβ是阿尔茨海默氏病的阳性指标,另一方面,低水平的tau和高水平的(x-≥41)Aβ是阿尔茨海默氏病的阴性指标疾病是一个指标。

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