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Aerosol formulations and aerosol delivery of butalbital, lorazepam, ipratropium, baclofen, morphine and scopolamine
Aerosol formulations and aerosol delivery of butalbital, lorazepam, ipratropium, baclofen, morphine and scopolamine
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机译:丁比妥,劳拉西m,异丙托品,巴氯芬,吗啡和东pol碱的气雾剂和气雾剂递送
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摘要
A liquid aerosol formulation comprising at least one thermally stable active ingredient selected from the group consisting of butalbital, lorazepam, ipratropium, baclofen, morphine, scopolamine, pharmaceutically acceptable salts and esters thereof and derivatives thereof. The liquid formulation can include an organic solvent such as propylene glycol and one or more optional excipients. The active ingredient can be present in an amount of 0.01 to 5 weight percent and the formulation can be heated to provide a vapor which forms an aerosol having a mass median aerodynamic diameter of less than 3 μm.
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