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Adsorbent for cytokine, method of adsorptive removal, and apparatus adsorptive removal

机译:细胞因子的吸附剂,吸附去除方法和装置吸附去除

摘要

The present invention provides an adsorbent for efficiently adsorbing and removing cytokine in liquid and a method for removing cytokine in liquid by the adsorbent. Also, the present invention provides an adsorber for removing cytokine in liquid. Specifically, an adsorbent for cytokine is obtained by immobilizing a compound having a log P value of at least 2.50 (P is the partition coefficient in an octanol-water system) on a water-insoluble carrier. By contacting a liquid containing cytokine with the adsorbent for cytokine, the cytokine in the liquid can be effectively adsorbed and removed. Furthermore, cytokine can be efficiently adsorbed and removed by an adsorber comprising a container having an inlet and an outlet for liquid and a means for preventing the adsorbent from flowing out of the container, which is filled with the adsorbent.
机译:本发明提供了用于有效地吸附和去除液体中的细胞因子的吸附剂以及通过该吸附剂去除液体中的细胞因子的方法。另外,本发明提供了用于去除液体中的细胞因子的吸附剂。具体地,通过将​​log P值至少为2.50(P是辛醇-水系统中的分配系数)的化合物固定在水不溶性载体上来获得细胞因子的吸附剂。通过使含有细胞因子的液体与细胞因子的吸附剂接触,可以有效地吸附和去除液体中的细胞因子。此外,细胞因子可以通过吸附器被有效地吸附和去除,该吸附器包括具有用于液体的入口和出口的容器以及用于防止吸附剂从填充有吸附剂的容器流出的装置。

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