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Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
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机译:T细胞免疫应答cdna7(tirc7)在血管生成和抗血管生成治疗中的用途
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摘要
A novel use of T-cell immune response cDNA 7 (TIRC7) in angiogenic and anti-angiogenic therapy is described. Provided are agents such as anti-TIRC7 antibodies and methods of treatment which through modulating the activity of TIRC7 can be used for enhancing or suppressing angiogenesis and/or neovascularization, an important feature in many pathological conditions including wound healing, solid tumors, developing metastases, ischemic heart diseases and diabetic retinopathy. Furthermore, diagnostic methods for the detection of such diseases using TIRC7 specific agents are provided.
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