Method for diagnosing and treating breast cancer

摘要

A method of evaluating progress of a cancer comprises calculating a prognostic index by selecting coefficients for each of a plurality of nuclear pleomorphic features using a numerical regression, such that the selected coefficients provide a correlation extremum to times to recurrence. A prognostic index is calculated by measuring nuclear pleomorphic features in a patient, and multiplying the observed values by the corresponding selected coefficients. The resulting prognostic index can provide a superior prediction of the likely time to recurrence in the patient.