Vortex flow atmospheric pressure chemical ionization source for mass spectrometry

摘要

An ion source for use in mass spectrometry, and particularly an atmospheric pressure chemical ionization (APCI) source, comprises a chamber having a central axis, a sample conduit that includes a sample outlet communicating with the chamber, an ionizing device disposed downstream from the sample conduit, and a gas conduit that includes a gas outlet communicating with the chamber. The gas conduit defines a flow path directed into the chamber. The flow path includes a velocity component that is tangential with respect to the central axis of the chamber. The gas so directed into the chamber establishes a vortex gas flow therein, forcing the sample emitted from the sample outlet to flow toward the heated wall of the chamber. Vaporization of the sample prior to ionization is consequently improved.