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Protease inhibitors of the coagulation cascade isolated from Dysidea sponges
Protease inhibitors of the coagulation cascade isolated from Dysidea sponges
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机译:从Dysidea海绵分离的凝血级联的蛋白酶抑制剂
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摘要
The present invention is directed toward a composition comprising a compound isolated from Dysidea species sponges that is capable of inhibiting serine proteases of the coagulation cascade. In particular, this composition inhibits the TF/VIIa complex of the coagulation cascade. The invention is also directed toward methods employing this composition as a part of anticoagulant therapy.
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