Hepp, a novel gene with a role in hematopoietic and neural development

摘要

The invention is directed to an isolated gene and protein product, designated Hepp, which has a role in mammalian hematopoiesis and neural function, and is further directed to a genetically modified non-human mammal that is homozygous or heterozygous for a disruption in the endogenous Hepp gene.