首页> 外国专利> 4-AMINO-5,6-SUBSTITUTED THIOPHENO 2,3-D PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS

4-AMINO-5,6-SUBSTITUTED THIOPHENO 2,3-D PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS

机译：4-AMINO-5,6-取代的噻吩[2,3-D]嘧啶，包含相同的药物组合物及其在治疗或预防PDE7B介导的疾病和状况中的用途

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摘要

The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7_B(PDE7_B). Diseases and conditions mediated by PDE7_Binclude osteoporosis, osteopenia and asthma.

机译：本发明涉及4-氨基-5,6-取代的噻吩[2,3-d]嘧啶，包含它们的药物组合物及其在治疗或预防由磷酸二酯酶7 _{B 介导的疾病和病症中的用途。 Sub>（PDE7 _{B ）。 PDE7 _{B 介导的疾病和病症包括骨质疏松症，骨质减少和哮喘。}}}

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公开/公告号US6849638B2

专利类型
公开/公告日2005-02-01

原文格式PDF
申请/专利权人 ANDREAS STOLLE;DONALD E. BIERER;YUANWEI CHEN;DONGPING FAN;BARRY HART;MARY KATHERINE MONAHAN;WILLIAM J. SCOTT;
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申请/专利号US20020136575
发明设计人 ANDREAS STOLLE;DONALD E. BIERER;YUANWEI CHEN;DONGPING FAN;BARRY HART;MARY KATHERINE MONAHAN;WILLIAM J. SCOTT;
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申请日2002-04-29
分类号C07D49514;C07D49504;A61K31519;A61P1706;A61P1106;
国家 US
入库时间 2022-08-21 22:19:33

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