Aerosol formulations for pulmonary Administration of Drugs that produce a Systemic effect

摘要

Pharmaceutical composition comprising a drug spray in a solution in a mixture of a hydrofluoroalkane propellant and one or more cosolvents where drops of liquid spray to administer the Act the inhaler with a particle size of between 0.5 and 2.5 microns MicronWith the Mass median aerodynamic diameter of approximately 1 to 2 microns and the fine Particle fraction is at least 30%. Claim 4: a Pharmaceutical formulation according to claim 1, wherein Said propellant that includes one or more hfas seleccina (n) between HFA 134a and hfa227.