Topical Pharmaceutical formulation Stabilized with content of ketoprofen

摘要

Described is a particularly topical Pharmaceutical formulation stabilized gel and Spray Gel containing ketoprofen and dexketoprofen s (+) isomer or mixtures of the two isomers, together with a special UV filter and a specific Antioxidant in defined quantities.The Formula allows a Photostability of the active principle, has no, or a very low Irritant effect on the skin, are well tolerated showing adequate penetration through the skin and an optimal Analgesic efficacy.Claim 1: Topical Pharmaceutical formulation Stabilized with content of ketoprofen, characterized in that it comprises: a) Ketoprofen in free acid form or its pharmaceutically acceptable salts or mixtures thereof; (b) sulisobenzono Butyl Hydroxy anisole; (c), possibly in combination with e Xcipientes pharmaceutically acceptable.