Topical formulations containing ketoprofen stabilized with sulisobenzone

摘要

Topical pharmaceutical formulations are described, in particular gels and spray gel, containing ketoprofen or its S(+) isomer dexketoprofen or mixtures of the two isomers, together with a special UV filter and a special antioxidant in defined quantities. The formulations allow the photostability of the active ingredient, they have no, or very low, irritant effect on the skin, are well tolerated and show an adequate penetration across the skin and an optimum analgesic efficiency.