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Modified recombinant Cells (ARCS) for the production and Application of antiviral agents, adjuvants and Vaccine accelerants

机译:用于生产和应用抗病毒剂,佐剂和疫苗促进剂的改良重组细胞(ARCS)

摘要

Compositions of cytokines, chemokines and / or active, processing and Application of cytokines / chemokines and composicones or active. Methods of treatment and methods to accelerate an immune response that include the Administration of a modified recombinant CELL (ARC) which contains compositions of cytokines or chemokines and / or humasnos animals.Claim 1: a modified recombinant CELL (ARC) which comprises at least a heterologous Gene, which encodes a chemokine or a cytokine. Claim 3: The Arc according to claim 2, wherein the heterologous Gene encodes IFN gamma. Claim: The 9 Arc according to claim 8, wherein the microbial cell is Pseudomonas fluorescens.The Method of claim 21: 19 according to the demand, which also includes the Administration of Antigen or an immunogenic before, simultaneously with, or subsequent to the Administration of a Composition of Arc.The Method of claim 29: 28 according to the demand, which also includes the Administration of chemotherapeutic agents, and Optionally, tumors or cancer antigens.
机译:细胞因子,趋化因子和/或活性成分,细胞因子和趋化因子或复合物或活性成分的加工和应用。治疗方法和加速免疫应答的方法包括施用包含细胞因子或趋化因子和/或腐殖质动物组合物的修饰的重组CELL(ARC)。权利要求1:至少包含至少一种修饰的重组CELL(ARC)编码趋化因子或细胞因子的异源基因。 3.根据权利要求2所述的电弧,其中所述异源基因编码IFNγ。 9.根据权利要求8的9弧,其中所述微生物细胞是荧光假单胞菌。根据要求的权利要求21:19的方法,其还包括在施用之前,同时或之后施用抗原或免疫原性30.根据要求的权利要求29:28的方法,其还包括化学治疗剂的施用,以及任选地肿瘤或癌抗原的施用。

著录项

  • 公开/公告号AR041548A1

    专利类型

  • 公开/公告日2005-05-18

    原文格式PDF

  • 申请/专利权人 DOW AGROSCIENCES LLC;

    申请/专利号AR2003P103652

  • 发明设计人

    申请日2003-10-07

  • 分类号C12N1/21;C12N1/15;C12N15/19;C12N15/20;C12N15/63;A61K39/02;A61K39/12;A61K39/00;A61K38/21;A61K31/739;A61K39/085;A61K39/08;A61K39/285;A61K39/07;A61P1/00;A61P37/04;A61P35/00;C07K14/24;C07K14/31;C07K14/32;C07K14/33;C07K14/37;C07K14/07;C07K14/08;C12N1/21;C12R1/39;

  • 国家 AR

  • 入库时间 2022-08-21 22:18:48

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