Diacid (4S, 8S) - and (4R, 8R) - 4 - methyl - nitrobencil P - 8 - - - - triaza 3,6,9 3N, 6n, 9N - tricarboximetil undecanoic enantiomerically Pure - 1.11 - and its derivatives, Process for their Preparation and use for preparing Pharmaceutical agents

摘要

The corresponding purity compound (1) in another set of equations,Where: Z is a hydrogen atom, or the metal ion equivalent of atom number 21-29, 31, 32, 37-39, 42-44, 46, 47, 49, 58-71, 75, 77, 82 or 83, and a is a group;R is a biomolecule, linked together by a functional group, or a C1-25 linear or separator radical tar, saturated or unsaturated or unsaturated, optionally interrupted by one to six atoms from O, or phenyl, group -NHCO,- er...Or the rest of a formula group (2) and / or - NH - (C = s) - NH,Alternatively, one to six groups of carbon compounds, hydroxyl groups, aminobenzene groups or other functional groups through which biomolecules and their salts can be combined with organic or inorganic bases can be substituted, The condition is that the radical tar contains at least one biomolecule linked by a functional group, and at least two ZS are equivalent to metal ions. 2. Procedures for the preparation and use of agents for radiation diagnosis, radiotherapy or Rmn diagnosis.