INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND THEIR ADMINISTRATION AS MEDICAMENTOUS FORM

摘要

The present invention relates to novel classes of compounds, which are inhibitors of interleukin-1-beta converting enzyme (ICE), to a method for the preparation thereof, and to pharmaceutical compositions containing these compounds. The compounds and the pharmaceutical compositions according to the invention are suitable for the inhibition of ICE activity and can be used as agents against interleukin-1- (IL-1), apoptosis, inducing interferon gamma (IGIF) and interferon (IFN-gamma), including inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases and degenerative diseases.