Compound, process for the preparation and use thereof, method for treating a human or animal subject suffering from, or susceptible to, an inflammatory condition, and, pharmaceutical composition.

摘要

"COMPOUND, PROCESS FOR PREPARATION AND USE OF THE SAME, METHOD FOR THE TREATMENT OF A HUMAN OR ANIMAL SUBJECT THAT IS SUFFICIENT OF, OR THAT IS SUSTAINABLE, AN INFLAMMATORY CONDITION". Compounds of formula (I) wherein: R1 represents substituted or unsubstituted heteroaryl; Y represents - (CRnaRnb) n-: Rna and Rnb are each independently hydrogen or C1-6 alkyl; n is an integer from 0 to 5; R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 and R4 each independently represent hydrogen or C1-6 alkyl; R7 represents hydrogen or C1-6 alkyl; R8 represents hydrogen or C1-6 alkyl; and their salts and solvates; they are CCR3 antagonists and are therefore indicated to be useful in therapy.