首页> 外国专利> Quinazoline derivative or a pharmaceutically acceptable salt thereof, process for preparing it, pharmaceutical composition, use of said derivative or salt thereof, method for producing an antiproliferative effect on a warm-blooded animal in need of such treatment, and , compound or a salt thereof.

Quinazoline derivative or a pharmaceutically acceptable salt thereof, process for preparing it, pharmaceutical composition, use of said derivative or salt thereof, method for producing an antiproliferative effect on a warm-blooded animal in need of such treatment, and , compound or a salt thereof.

机译:喹唑啉衍生物或其药学上可接受的盐,其制备方法,药物组合物,所述衍生物或其盐的用途,对需要这种治疗的温血动物产生抗增殖作用的方法及其化合物或盐。

摘要

"QUINAZOLIN DERIVATIVE OR SALT OF THIS PHARMACEUTICALLY ACCEPTABLE, PROCESS FOR THE PREPARATION OF THE SAME, PHARMACEUTICAL COMPOSITION, USE OF THE DERIVATIVE DISTRICT OR SALT, METHOD OF PRODUCTING AN ANTI-PROLIFERENT EFFECT ONLY IN AN ANIMAL PROLIMENTALLY AND, COMPOUND OR A SALT OF THIS ". The invention relates to quinazoline derivatives of Formula (I) wherein each of Q ^ 1 ^, Z, R ^ 1 ^ and Q ^ 2 ^ have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors that are sensitive to inhibition of erbB receptor tyrosine kinases.
机译:“喹诺林灵这种药学上可接受的衍生物或盐,其制备方法,药物组合物,衍生物或盐的使用,在动物体内仅产生盐的抗增生作用的方法以及全部或全部”。本发明涉及式(I)的喹唑啉衍生物,其中Q ^ 1 ^,Z,R ^ 1 ^和Q ^ 2 ^具有说明书中定义的任何含义;制备方法,包含它们的药物组合物及其在制备用于预防或治疗对抑制erbB受体酪氨酸激酶敏感的肿瘤的抗增殖剂的药物中的用途。

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