A method of preparing solid two-layer coated dosage forms comprising a water-insoluble polymer and a water-soluble pore-forming agent.

摘要

"METHOD FOR PREPARING SOLID DOSAGE FORMS COVERED IN TWO LAYERS UNDERSTANDING A WATER INSOLUBLE POLYMER AND A WATER SOLUBLE PORE FORMER". This invention provides a method for preparing a coated solid dosage form, wherein a solid dosage form, such as a tablet pressed with an active agent dispersed therein, is coated at least twice with a coating solution comprising a water-insoluble coating polymer and a water-soluble pore-forming agent being dried after at least the first coating step. The method of the present invention allows the production of solid, coated dosage forms and drying thereof using very short drying times. The coated solid dosage forms produced in accordance with the present invention have been found to have extended and extended release characteristics.