Crystalline substance for solid oral medicine and solid oral medicine for the treatment of dysuria containing the same

摘要

"CRYSTALINE SUBSTANCE FOR SOLID ORAL MEDICINAL PRODUCT AND SOLID ORAL MEDICINAL PRODUCT FOR TREATMENT OF DYNAMICS CONTAINING THE SAME". A crystalline solid oral medicament comprising an indoline compound (KMD-3213) and exerting a β-1 -adrenaline receptor blocking activity is useful as a therapeutic agent for dysuria and is represented by the formula (I) wherein, in the powder X-ray diffraction pattern, the compound is characterized by major peaks of 5.5 198 0.2 198, 6.1 198 sym 0.2 198, 9.8 198 sym 0.2 198, 11.1 sym 0.2 198, 12.2 198 sym 0.2 198 , 16.4 198 sym 0.2 sym, 19.7 198 sym 0.2 198 and 20.0 198 sym 0.2 198 as 2 sym. A solid oral medicament for treating dysuria containing the crystalline substance as an active ingredient is further proposed.