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Compound, process for preparing a compound, process for preparing a stereoisomer of a compound, composition for the treatment of viral diseases, and composition for the treatment of hepatitis b

机译:化合物,化合物的制备方法,化合物的立体异构体的制备方法,用于治疗病毒性疾病的组合物和用于治疗乙型肝炎的组合物

摘要

"COMPOUND, PROCESS FOR PREPARING A COMPOUND, PROCESS FOR PREPARING A COMPOUND STEREOISMER, COMPOSITION FOR THE TREATMENT OF VIRAL DISEASES, AND COMPOSITION FOR THE TREATMENT OF HEPATITIS B". The present invention relates to (+) - trans-isomers of (1-phosphonomethoxy-2-alkylcyclopropyl) methyl nucleoside derivatives of formula (1) which are useful as an antiviral agent (particularly against hepatitis B virus) pharmaceutically acceptable salts, hydrates or solvates thereof, and processes for the preparation of stereoisomers of the compounds of formula (1), and a composition for the treatment of viral diseases (particularly against hepatitis B virus) comprising (+) - trans -isomer of the compound of formula (1), its pharmaceutically acceptable salt, hydrate or solvate as an active substance.
机译:“化合物,制备化合物的过程,制备复合立体异构体的过程,用于治疗病毒性疾病的组合物和用于治疗乙型肝炎的组合物”。本发明涉及式(1)的(+)-(1-膦酰基甲氧基-2-烷基环丙基)甲基核苷衍生物的(+)-反式异构体,其用作抗病毒剂(特别是针对乙型肝炎病毒)可药用盐,水合物或溶剂化物,式(1)化合物的立体异构体的制备方法以及用于治疗病毒性疾病(特别是针对乙型肝炎的病毒)的组合物,其包含式(1)化合物的(+)-反式异构体),其药学上可接受的盐,水合物或溶剂化物作为活性物质。

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