Methods for producing an antiangiogenic and / or vascular permeability reducing effect in a warm-blooded animal and for treating cancer in a warm-blooded animal, pharmaceutical composition, kit, and use of zd6474 or an acceptable pharmaceutically acceptable salt thereof and gemcitabine

摘要

"METHODS FOR PRODUCING AN ANTIGIOGENIC EFFECT AND / OR VASCULAR PERMEABILITY REDUCER IN A HOT BLOOD ANIMAL AND FOR TREATMENT OF CANCER IN A HOT BLOOD ANIMAL, PHARMACEUTICAL COMPOSITION, K64, AND FACE USE OF ZD ALATE EVEN AND GENCITABIN ". The present invention relates to a method for producing an antiangiogenic and / or vascular permeability reducing effect in a warm-blooded animal, such as a human being optionally treated with ionizing radiation, particularly a method for treating cancer, particularly a cancer involving a solid tumor comprising administering ZD6474 in combination with gemcitabine; a pharmaceutical composition containing ZD6474 and gemcitabine; a combined product containing ZD6474 and gemcitabine for use in a method of treating a human or animal by therapy; a kit containing ZD6474 and gemcitabine; the use of ZD6474 and gemcitabine in the manufacture of a medicament for use in producing an antiangiogenic and / or vascular permeability reducing effect in a warm-blooded animal, such as a human being optionally treated with ionizing radiation.