首页> 外国专利> Method for producing polyunsaturated fatty acids in transgenic organisms to contain at least a delta-9 elongase and desaturase Delta - 8 - and if necessary alsoA Delta - desaturase; nucleotide sequences of delta - desaturase - 8

Method for producing polyunsaturated fatty acids in transgenic organisms to contain at least a delta-9 elongase and desaturase Delta - 8 - and if necessary alsoA Delta - desaturase; nucleotide sequences of delta - desaturase - 8

机译:在转基因生物中产生多不饱和脂肪酸的方法,所述多不饱和脂肪酸至少包含Δ9延伸酶和去饱和酶Δ8-,必要时还包含Δ-去饱和酶; δ-去饱和酶-8的核苷酸序列

摘要

The present Invention relates to an improved process for the specific production of polyunsaturated fatty acids w-3 and w-6 and conduct Production trigliceriWith an increased content of unsaturated fatty acids in particular Fatty Acids w-3 and w-6 having at least two double Bonds and a chain length of 20 or 22 Atoms of CarboNot.The Invention relates to the production of a transgenic organism, preferably a transgenic plant or microorganism trangenico, which has an increased content of Fatty AcidsOils, Lipids containing C20 fatty acids - C22 - A5 with a double Bond, 7.8,10 respectively due to the expression of a desacurasa A8 and A9 elongase organisms such as plants or Algae Isochrysis galbana preferably as Euglena gracilis.The Invention also relates to a process for the production of polyunsaturated fatty acids such as arachidonic acid icosapentanoico,Dosapentanoico or dosahexanoico through coexpression of - 8 - 9 desaturase, a - to - 5 - elongase and desaturase in organisms such as plants or microorganisms.
机译:本发明涉及一种改进的方法,用于特定地生产多不饱和脂肪酸w-3和w-6,并进行生产trigliceri,其中不饱和脂肪酸的含量增加,特别是具有至少两个两倍的脂肪酸w-3和w-6。碳键的键和20或22个原子的链长。本发明涉及转基因生物的生产,优选转基因植物或微生物转基因,其脂肪酸含量增加。油,含C20脂肪酸的脂类-C22-A5由于desacurasa A8和A9延伸酶生物例如植物或藻类等渗线藻的表达优选地具有Euglena gracilis,其双键分别为7.8、10。本发明还涉及生产多不饱和脂肪酸例如花生四烯酸的方法。通过在诸如pla的生物体中共表达-8-9去饱和酶,α-至-5-延伸酶和去饱和酶来形成酸性二十碳五烯酸,二十碳五烯酸或十二碳六烯酸nts或微生物。

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