Heterocyclic compounds of the type 1,4 diazepam - 2 - ona replacedInhibitors of the Enzyme dipeptidilpeptidasa IV (COP IV); Pharmaceutical Composition and its use for preparing medicine to treat Type 2 diabetes, hyperglycemia, obesity, trast

摘要

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.