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Antibacterial anti-plaque anti-toothpaste oral care

机译:抗菌抗牙斑抗牙膏口腔护理

摘要

An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces. Suitable enhancing agents are anionic polymers such as a maleic acid-methyl vinyl ether copolymer or a polymer containing phosphonic groups. Also disclosed are compositions comprising (1) the noncationic antibacterial agent and the enhancing agent, (2) the polyphosphate anticalculus agent and the noncationic antibacterial agent and (3) the enhancing agent and polyphosphate anticalculus agent effective against any antibacterial agent.
机译:口腔组合物,例如洁牙剂,漱口水,锭剂或口香糖,其含有多磷酸盐防牙结石剂,例如四碱金属焦磷酸盐和与其相容的抗菌防斑剂。防斑剂是基本上不溶于水的非阳离子抗菌剂,例如2,4,4'-三氯-2'-羟基二苯醚(三氯生)。抗菌增强剂的存在可优化抗牙菌斑的有效性,该增强剂可增强所述抗菌剂向口腔表面的递送以及在口腔表面的保留。合适的增强剂是阴离子聚合物,例如马来酸-甲基乙烯基醚共聚物或含有膦基的聚合物。还公开了包含(1)非阳离子抗菌剂和增强剂,(2)聚磷酸盐抗结石剂和非阳离子抗菌剂,和(3)对任何抗菌剂有效的增强剂和聚磷酸盐抗结石剂的组合物。

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